In the quest for better health, energy, or weight loss, many people turn to supplements. However, not all supplements are safe — even those labeled “natural” can carry serious risks. Doctors are increasingly warning that certain over-the-counter supplements can damage the heart and liver, sometimes leading to life-threatening conditions.
Here are five supplements you should be extremely cautious about.
1. Green Tea Extract (in High Doses)
Green tea itself is healthy, but concentrated green tea extract found in weight-loss pills can be dangerous. High doses of catechins — especially EGCG (epigallocatechin gallate) — can cause liver toxicity. Over time, this may lead to inflammation, jaundice, or even acute liver failure.
Doctors warn: If you use green tea supplements, stick to low doses and avoid combining them with alcohol or other liver-affecting substances.
2. Bitter Orange (Synephrine)
Commonly found in “fat-burning” and “energy-boosting” supplements, bitter orange contains synephrine, a compound similar to ephedrine. It can raise blood pressure and heart rate, dramatically increasing the risk of heart attack or stroke, especially during exercise.
Doctors warn: Those with high blood pressure or heart conditions should avoid bitter orange altogether.
3. Anabolic Steroid-Like Supplements
Some bodybuilding products secretly contain steroid-like substances marketed as “prohormones” or “muscle enhancers.” These can severely strain the liver and disrupt hormone balance, leading to liver injury, heart enlargement, and long-term cardiovascular problems.
Doctors warn: Always check for FDA warnings or bans before using any performance-enhancing supplement.
4. Kava
Used for stress relief and anxiety, kava is derived from a plant native to the South Pacific. While it can promote relaxation, numerous studies have linked kava use to severe liver damage — including cases that required liver transplants.
Doctors warn: Avoid kava if you already take medications that affect the liver or drink alcohol regularly.
5. Red Yeast Rice
Marketed as a “natural alternative” to statins for lowering cholesterol, red yeast rice can actually contain a statin-like compound called monacolin K. This can lead to muscle damage, kidney strain, and even liver failure, especially when taken in high doses or alongside prescription statins.
Doctors warn: Regular monitoring of liver function is essential for anyone taking this supplement.
Final Thoughts
Supplements can support your health — but only when used responsibly. Many products on the market are unregulated and may contain harmful levels of active ingredients or hidden compounds.
Before starting any new supplement, consult your doctor or pharmacist — especially if you have liver, heart, or kidney conditions. Natural doesn’t always mean safe, and being informed could save your life.
